产品货号：
Z11021
中文名称：
APBB1抗体
英文名称：
Anti-APBB1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-APBB1 Antibody |
| 指标别名 | APBB1;FE65;Protein Fe65;RIR |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | APBB1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human FE65 (21-56aa ALSLPLPLHAAHNQLLNAKLQATAVGPKDLRSAMGE),different from the related mouse sequence by two amino acids,and from the related rat sequence by three amino acids. |
| 实际分子量 | 77KD/100KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | APBB1 is also known as RIR or FE65.The protein encoded by this gene is a member of the Fe65 protein family.It is an adaptor protein localized in the nucleus.It interacts with the Alzheimer's disease amyloid precursor protein (APP),transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein.APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation.This encoded protein could play an important role in the pathogenesis of Alzheimer's disease.It is thought to regulate transcription.Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression.Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Uniprot ID | O00213 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | amyloid beta (A4) precursor protein-binding,family B,member 1 (Fe65) |
| 蛋白名全称 | Amyloid beta A4 precursor protein-binding family B member 1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
相关搜索：APBB1抗体，APBB1多抗，Anti-APBB1 Antibody